Targeted enrichment with Watchmaker TAPS+ distinguishes immune cell types by methylation signal in concordance with WGS (Broad Clinical Labs)
Highlights
Unified genomic and epigenomic profiling: TAPS+ enables simultaneous detection of methylation, SNVs, and structural variants from a single NGS library
Concordant performance across workflows: Methylation signals from targeted enrichment align closely with WGS, enabling flexible assay design without compromising data quality
Biologically meaningful resolution: TAPS+ methylation profiles support scalable applications such as cell-type deconvolution and translational research
Highly sensitive, scalable, and robust chemistry with respect to performance with challenging clinically relevant sample types, such as FFPE and low inputs...