Improved whole transcriptome sequencing for challenging clinical samples: A streamlined alternative to targeted RNA-seq

This case study presents CellCarta's evaluation of Watchmaker RNA Library Prep with Polaris Depletion as an alternative to targeted RNA-seq across whole blood and FFPE samples.

• Robust and reproducible whole transcriptome libraries with efficient depletion from high-quality RNA, whole blood, and degraded FFPE tissue, across broad inputs.
• Save ~11 hours of processing time compared to targeted RNA-seq workflows.
• More genes detected, including protein-coding genes and lncRNAs beyond the reach of exome-targeted approaches.

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