CASE STUDY

Fusion detection in pediatric oncology: Insights from whole transcriptome sequencing

This case study showcases the sensitive performance of the Watchmaker RNA Library Prep Kit with Polaris® Depletion for fusion detection in clinical oncology applications.

Highlights

  • Detected more clinically relevant fusions from FFPE and low-input samples compared to alternative kits
  • Delivered faster turnaround and higher sensitivity without compromising data quality
  • Integrated seamlessly into existing bioinformatics pipelines at a leading pediatric hospital
Read the application note Enzymatic fragmentation enables scalable preparation of high-quality FFPE libraries with minimal artifactsRead the application note Enzymatic fragmentation enables scalable preparation of high-quality FFPE libraries with minimal artifacts

Discover more with Watchmaker

RNA Library Prep Kits with Polaris® Depletion

Prepare libraries in under 4.5 hours with as little as 1 ng with a solution that includes tailored steps for FFPE processing...

mRNA Library Prep Kits

Prepare high-quality libraries in under 5 hours with as little as 2.5 ng...

DNA Library Prep Solutions

Rapid workflows to address all sample types and yield high conversion rates, reduced bias and artifacts, and reproducible results...