CASE STUDY

Fusion detection in pediatric oncology: Insights from whole transcriptome sequencing

This case study showcases the sensitive performance of the Watchmaker RNA Library Prep Kit with Polaris® Depletion for fusion detection in clinical oncology applications.

Highlights

  • Detected more clinically relevant fusions from FFPE and low-input samples compared to alternative kits
  • Delivered faster turnaround and higher sensitivity without compromising data quality
  • Integrated seamlessly into existing bioinformatics pipelines at a leading pediatric hospital

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Read the application note Enzymatic fragmentation enables scalable preparation of high-quality FFPE libraries with minimal artifactsRead the application note Enzymatic fragmentation enables scalable preparation of high-quality FFPE libraries with minimal artifacts

Discover more with Watchmaker

mRNA Library Prep Kits

Prepare high-quality libraries in under 5 hours with as little as 2.5 ng...

RNA Library Prep Kits with Polaris® Depletion

Prepare libraries in under 4.5 hours with as little as 1 ng with a solution that includes tailored steps for FFPE processing...

DNA Library Prep Solutions

Rapid workflows to address all sample types and yield high conversion rates, reduced bias and artifacts, and reproducible results...