Transcriptomics provides a snapshot of cellular activity at specific points in time and in response to environmental stimuli. It aims to characterize both protein-coding and non-coding transcripts (and the variation therein) and quantify their complex ebb and flow. This allows researchers to unravel biological mechanisms, detect and monitor cancer and other diseases, and validate biomarkers and drug responses.

There is a need for RNA library preparation solutions that are highly sensitive, scalable, robust with respect to performance with challenging clinically relevant sample types, such as FFPE and low inputs. Our portfolio delivers in all of these areas, enabling cutting edge research and applications in the transcriptomics space.

• Watchmaker RNA Library Prep Kits with Polaris^® Depletion for improved sensitivity with FFPE and low-inputs using a rapid library prep workflow
• Watchmaker mRNA Library Prep Kits for library prep in < 5 hours with as little as 2.5 ng
• Watchmaker RNA Library Prep Kits for the streamlined prep of total RNA libraries for target enrichment applications

• Increase sensitivity with FFPE and low-input samples
• Generate high-quality libraries with rapid, easily automated workflows
• Improve automatability with fewer cleanups and handling steps
• Discover the value of a reverse transcriptase engineered specifically for RNA sequencing

Figure 1. Truly single-day RNA library prep. The Watchmaker RNA portfolio offers three streamlined workflow options to address any RNA sequencing application and associated sample type. Reduced incubation times and fewer purification and handling steps makes all three workflows highly automatable and easily completed in a single workday.